Clinical Trials

UVA Health System frequently opens new clinical trials, offering your patients the latest investigational treatments.

For a complete list of active cancer trials and study coordinator contact information, visit our newly launched Find a Clinical Trial website. If you have patients who may be eligible to participate in a cancer clinical trial, please email




New Trials Available at UVA

Breast Oncology (IRB-HSR #19900)

Focused Ultrasound Therapy to Augment Antigen Presentation and Immune-Specificity of Checkpoint Inhibitor Therapy with Pembrolizumab in Metastatic Breast Cancer

Primary Investigator: Patrick Dillon
Clinical Research Coordinator: Jessica Zareno

Advanced Solid Tumors (IRB-HSR #19972)

Phase I Study of C6 Ceramide NanoLiposome in Patients with Advanced Solid Tumors (NCT02834611)

Primary Investigator: Robert Dreicer
Clinical Research Coordinator: Susan Jones

Hematologic Malignancies (IRB-HSR #19332)

A Multi-Center, Open-Label, Study to Evaluate the Safety and Efficacy of Ublituximab (TG-1101) in Combination with TGR-1202 for Patients Previously Enrolled in Protocol UTX-TGR-304 (NCT02656303)

Primary Investigator: Craig Portell
Clinical Research Coordinator: Michal Ande

Lymphoma (IRB-HSR #19675)

A Randomized Double-Blind Phase III Study of Ibrutinib During and Following Autologous Stem Cell Transplantation Versus Placebo in Patients with Relapsed or Refractory Diffuse Large B-cell Lymphoma of the Activated B-cell Subtype

Primary Investigator: Karen Ballen
Clinical Research Coordinator: Kristen Johnson

Neuroblastoma (IRB-HSR #19031)

Treatment of Neuroblastoma and GD2-Positive Tumors with Activated T Cells Armed with OKT3 X Humanized 3F8 Bispecific Antibodies (GD2Bi): A Phase I/II Study

Primary Investigator: Daniel Lee
Clinical Research Coordinator: Candace Hudspeth

Type 1 Diabetes (IRB-HSR #18237)

Clinical Research Study Examining the Impact of Fitness and Mineralocorticoid Receptor Blockade on Vascular Dysfunction in Adults with Type 1 Diabetes

Primary Investigator:  Eugene Barrett
Clinical Research Coordinator: Leona Hartline

Acute Myeloid Leukemia (IRB-HSR #19366)

A Randomized, Double-Blind Phase 3 Study of Vadastuximab Talirine (SGN-CD33A) Versus Placebo in Combination with Azacitidine or Decitabine in the Treatment of Older Patients with Newly Diagnosed Acute Myeloid Leukemia  (NCT02785900)

Primary Investigator: Michael Keng
Clinical Research Coordinator: Amelia Hodson

Myelodysplastic Syndrome (IRB-HSR #19703)

A Phase 3 International, Randomized, Controlled Study of Rigosertib Versus Physician¿s Choice of Treatment in Patients with Myelodysplastic Syndrome After Failure of a Hypomethylating Agent (NCT02562443)

Primary Investigator: Michael Keng
Clinical Research Coordinator: Amelia Hodson